USPTO Patents Application 10006014

AMENDMENTS TO THE CLAIMS

This listing of claims will replace all prior versions, and listings, of claims in the
application.

1 . (Currently Amended) A method for selectively inhibiting Cox-2 relative to Cox-1 ef
treating pain and inflammation comprising the steps of:

administering a pre-determined dose of processed Morinda citrifolia juice to a

an amount of about 2.3 1 percent by volume ; and
limiting undesired COX-1 inhibition relative to COX-2 inhibition by varying the
conc e nt rati on of said dose depending upon the age, w e ight, gen e ral h e alth,
diet, and sex of said patient, as well as the time and route of
administration, rate of excr e tion, drug combination, and the sev e rity of the
particular disease being treated .

2. (Cancelled)

3. (Original) The method of claim 1, wherein the Morinda citrifolia is in liquid form.

4. (Original) The method of claim 1, wherein the Morinda citrifolia is included as an
ingredient in a food product.

patient two times per day wherein

-said Morinda citrifolia juice is present in

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5.

(Original) The method of claim 1, wherein the Morinda citrifolia is in capsule form.

6. (Original) The method of claim 1, wherein said dose of Morinda citrifolia inhibits the
production of COX-2 related prostaglandins that cause pain and inflammation and
inhibits to a lesser extent, the production of COX-1 related prostaglandins.

7. (Original) The method of claim 1, wherein said dose of Morinda citrifolia is administered
at a predetermined concentration.

8. (Original) The method of claim 7, wherein said Morinda citrifolia is included as an
ingredient in another food product.

9. (Currently Amended) A method of treating pain and inflammation comprising the steps
of:

obtaining a quantity of Morinda citrifolia juice and pulp;
filtering the wet pulp from the juice;
pasteurizing the juice; and

providing a therapeutic dose of said Morinda citrifolia juice for consumption in
an amount between about 2 and 3 ounces, wherein said Morinda citrifolia
juice is present in an amount of about 2.3 1 percent by volume wherein
said dose is administ e red two to thre e times daily and wher e in the total
daily amount of Morinda citrifolia juice administered is less than 6 to limit
undesired COX-1 inhibition relative to COX-2 inhibition.

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1 0. (Original) The method of claim 9, wherein the Morinda citrifolia juice is included as an
ingredient in a food product.

11. (Cancelled)

12. (Currently Amended) A method of treating pain and inflammation comprising the steps
of:

obtaining a quantity of Morinda citrifolia juice and pulp;

filtering the wet pulp from the juice, wherein the wet pulp has a fiber content of

from 10% to 40%, by weight;
pasteurizing the pulp; and

providing a therapeutic dose of said Morinda citrifolia pulp for consumption by a
patient, wherein said Morinda citrifolia juice is present in an amount of
about 2.3 1 percent by volume wherein said dose is b e tween two to three
ounces that is administered two to three times daily for limiting undesired
COX- 1 inhibition relative to COX-2 inhibitionf-and

varying said dose dep e nding upon the age, weight, general h e alth, diet, and sex of
said pati e nt, as well as th e time and route of administration, rate of
excretion, drug combination, and the sev e rity of the particular disease

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1 3 . (Original) The method of claim 12, wherein the Morinda citrifolia pulp is included as an
ingredient in a food product.

14. (Cancelled)

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